FACILITIES & INSTRUMENTATION

Darwin PH09 stability Chamber

Key Features

  • Performance specifications exceeding FDA and ICH requirements
  • Excellent humidity control and avoids hot spots during mapping

Application

  • Stability studies of compound/formulation in development
  • Standardize ph/stability/solubility profiles of active pharmaceutical ingredients (api)
  • Compatibility studies to identify the best ingredients to enhance api performance across dosage forms

 

LV1 Low Volume Microfluidizer Homogenizer

Key Features

  • Small sample size requirements (1-6 ml)
  • Produces tunable nanoscale vesicles with narrowest particle size distribution for high-throughput drug screening and drug delivery

Application

  • Nanoencapsulation
  • Nanoemulsions
  • Nanosuspensions
  • Deagglomeration
  • Liposomes
  • Cell disruption (yeasts and plant cells)

 

Zetasizer Nano ZS

Application
Measurements of:

  • Size/electrophoretic mobility of proteins
  • Zeta potential of colloids/nanoparticles
  • Protein mobility
  • Microrheology of protein/polymer solutions
  • Molecular weight and second virial coefficient, a2, of macromolecules kd
  • Dls interaction parameter
  • Size detector for sec or fff

 

SOTAX CE 7smart USP Apparatus 4 – Flow Through Cell Dissolution

Application

  • Flexibility and ability to characterize the release properties of a wide variety of formulations for in-vitro drug release testing

 

LAMBDA 465 UV/Vis Spectrophotometer

Application:

  • determination of drug content to support formulation screening and quality control
  • PK studies
  • Determination of pKa and LogD

 

CytoViva Enhanced Darkfield Hyperspectral Microscope Imaging System

Application

  • Analytical confirmation of nano-scale materials and their interactions in solution, live cells, tissue, and materials based matrices
  • Provides spectral analysis of materials and biologicals imaged
  • Supports research in nano-drug delivery and nano-toxicology. Detects non-fluorescent and fluorescently labeled components in live cells and nano-materials